3. Avoid at All Costs: Mod-Mechanic Disasters

Some mod-mechanic combinations should be avoided entirely, especially in Hardcore or high-investment mapping:



Reflect + Delirium/Legion/Beyond.

If your build doesn't have 100% reflect immunity, avoid any “Physical/Elemental Damage Reflected” mods—especially in high-mob-density mechanics. One crit and you’re dead.



Temporal Chains + Blight/Legion

Temporal Chains reduce your action speed. This makes time-sensitive mechanics like Blight or Legion harder to POE currency complete.



Only run if your build is unaffected by curses or has a way to remove them.



Hexproof + Curse-Based Builds

If your build relies on curses (e.g., Enfeeble, Elemental Weakness, Despair), Hexproof maps essentially cut your damage or defenses in half.



Either reroll or use a Sextant to disable Hexproof temporarily.



No Regeneration + Righteous Fire / Self-Damage Builds

No regen maps completely shut down RF builds or buy POE2 Currency anything relying on regeneration.



Reroll or bring flasks that provide regen/life on use.